Americans should be able to get Novavax.
Americans should be able to get Novavax.
There is no good reason not to let people get Novavax after mRNA.
Hello everyone. This article is serving as an abridged version of a larger article to quickly explain some big ideas regarding Novavax in a very short amount of time.
I will be updating this with more information as is needed.
That being said, this is happening because TOMORROW, the 12th of Sept… The CDC will have its ACIP meeting to discuss COVID vaccines and decide who gets to have protection or not for the next year…
Basically deciding who will live or die… It’s like a death panel but with prevention.
Anywho…
This article is to help people who want to contact the ACIP members and bring this data to their attention… or at least we can know they have been made aware of it.
(edit, we are done contacting ACIP members. They approved Novavax for full use and told the FDA to deal with it and not kick it back to them.
Now we contact the FDA, will update shortly.)
Now, for some ungodly reason there is another meeting on the 22nd which could mean a lot of things from delays for Novavax or a different way to screw the public over with extra steps… wouldn’t be the first time.
Regardless, I wrote a tweet explaining the basic demands for the CDC on the 12th.
And people got busy writing public comments…
Make no mistake, the updated Novavax are in the country and ready to deliver.
So, were going to explain those ideas and a few extra to help everyone understand it
First, let’s start with how the vaccines work.
Each vaccine generates a different type of response… via different means.
Novavax is a traditional ‘protein based’ vaccine similar to the flu shots but the method to make it is sightly more involved than it’s made out to sound.
It’s really the simplest of all reactions but it’s not simple to make it.
Here is an explanation of how they make it…
Also, the use of ‘spike protein’ in the chart is slightly misleading as Novavax uses the parts of the spike protein called epitopes but not actual active spike protein.
Matrix-M has its own benefits.
Novavax’s vaccine uses a saponin based adjuvant that augments our immune systems in very beneficial ways… Saponins have been shown to be useful for fighting COVID.
It has a complex immune reaction that has been shown to stop infection in animals studies. The effect of this adjuvant should not be underestimated.
The Bill and Melinda Gates foundation has partnered to use Matrix M in Malaria vaccines and the first one is already headed to market.
It’s also showing promise in influenza vaccines…
This represents a paradigm shift in vaccines… The benefits of using this are many.
There is even the possibility it might help some people with Long COVID which we have seen anecdotally and a fairly decent theory exists as to why it occurs.
At the very least, we should figure it out.
Which means…
Novavax access after mRNA - Access for all.
It has been demonstrated that it is safe to get Novavax after mRNA many times.
These are results after boosting with a variety of COVID vaccines and then getting a Novavax booster on top of that.
Across multiple studies there are no examples of ill effects from switching to Novavax.
The most recent study not only demonstrated it’s safe, but creates the best response.
America is the ONLY country that limits access after getting mRNA.
And our regulatory bodies have never offered a reason for it.
There’s this concern Novavax might make people sick after mRNA but the data says the opposite is more likely true.
Novavax has half the adverse effects.
While many countries allow access post mRNA, widespread use is still limited.
Just to be clear… this is who has approved Novavax after mRNA.
And countries that have wide spread use have seen far fewer reported side effects of comparative COVID by a significant margin.
Novavax is twice as protective of hospitalization.
Since the widespread use of Novavax has been limited this study prepare a properly balanced comparative study with similar testing groups…
And it was found to be twice as protective of severe outcomes.
This is a worst case scenario situation but is critical to understand the greater picture.
But why can it do this when mRNA can’t?
Only Novavax creates upper resp. protection.
There’s no question mucosal protection is critical in our fight with COVID.
In a comparative study, only Novavax stopped viral replication in the nose by Day 2.
This will limit infection and transmission.
This could cut every aspect of COVID that is rapidly growing out of control.
Ultimately, widespread use of Novavax will slow mutation and that will make our tools more effective overall when we are quickly reaching a place that is untenable.
We need to make sure we can maintain the fullest protection possible.
Boosters needs to be available every six months.
Currently, waiting an entire year between booster is too far to remain protective.
Even Novavax, which has the longest protective window and without the gaps mRNA experiences, still requires a booster every 6-8 months.
Making booster available every six months will allow folks to maintain consistent protection and this will limit all negative effects of COVID.
And we need to make sure regulations follow the science and give Americans the best opportunity to avoid those negative effects.
New Primary series when switching to Novavax.
If someone is more than 150 days out from last mRNA vaccine, data shows they are essentially starting over. If they are only allowed one Novavax then they won’t experience the full protective benefits.
The data demonstrating this comes directly from the FDA.
Streamline under 12 Novavax.
Novavax has had its under 12 vaccine trials going (Project Hummingbird) and they explained at the last FDA hearing their pediatric vaccine is the same exact vaccine as the adults… So, that fits into the FDA/CDC plan to have one shot for everyone.
Studies have demonstrated this effect and it seems very positive.
This needs to be streamlined by the FDA/CDC to allow access ASAP.
The Novavax shots going to waste are the same that could be protecting our Children.
And we can’t say “We have the tools” and then simply not use them.
Novavax also works on immunocompromised.
Novavax was able to generate a response when the mRNA couldn’t.
This could single a life saving protective window for whole groups of people.
No more waste…
Originally vials were coming in ten shot vials and would have to be thrown away a few hours after opening which led to many wasted shots. They then moved to five dose vials which cut waste but did not remove it…
Novavax shots should not be going to waste.
So. now they are going to use single shot prepared vaccines, so no more waste.
Eric Topol has made his endorsement.
And it counts.
Eric Topol recently released a Substack discussing his position on Novavax and the updated vaccines in general… and though he expresses disappointment about how much protection they will offer, he does make it clear that Novavax was his preferred option. This highlights the value of the mix and match usage of COVID vaccines.
That alone is an extremely reasonable reason to open up access to anyone.
It has also been previously endorsed by our former COVID Czar.
Though the irony of him calling it “Novovax” is not lost on me.
More importantly though…
It’s important Novavax not be delayed.
Novavax has demonstrated an immune response against our new variants and, if the prototype is any indication, will continue to offer protection for variants mutations for at least a year, maybe longer.
Hopefully it will be a situation, as with Omicron, that simply an additional shot will shrink the antigenic range to continue being effective for an additional year.
The long lasting protective effects of Novavax cannot be denied.
Professionals speaking to the value of Novavax.
Jeff Gilchrist, a PhD scientist, published a twitter thread on Sept. 10th that explains in great detail the value of Novavax when compared to mRNA.
Daniel Park, Epidemiologist at GWU, has spoken to the success of Novavax as a vaccine platform with interpretations showing Novavax 9x better at preventing infection.
And here from the same study showing the safety profile.
Micheal Lin, Associate Prof. of Neurobiology & Bioengineering at Sanford, has interpreted similar results from the same studies.
If you’d like more information, accounts like ShellPhishOne carefully track the data.
I suggest reading through their threads if you want to have all the information.
And if that is somehow not enough for you after all this…. you can listen to my 4 min public comment/presentation at the last VRBPAC meeting regarding Novavax.
https://twitter.com/SocialFuzzer/status/1669397033231458304?s=20
Contacting the Committee.
I cannot make it more clear the need for a level of professionalism when reaching out to these people and I also cannot make it clearer that letters written organically are the most valuable… But we do want to centralize around simple ideas.
So, were going to back to the original ones…
- Novavax access after mRNA.
- Immediate access for all groups.
- Every six months availability.
- New primary series if more than 150 days out from last mRNA.
- Streamline under 12 Novavax
Reach out, be polite, and stress these simple points.
Also, stress that if they plan to delay Novavax until the meeting on the 22nd that we can continue sending these emails for the next 10 days until they vote to approve it.
EMAILS HAVE BEEN REMOVED.
Alright, that’s it for now…
There are a lot of things I could explain from here like IgG4 or imprinting but this will do for now but we do hold a spaces on Twitter/X four times a week from 5-7 pm pacific Mon-Thurs… you can follow me on Twitter/X here.
If you like what you’re seeing, you’re welcome to join us on discord.
https://discord.gg/HDw6N6xB
And if you really like what you’re seeing then you are welcome to make a donation via paypal or become a subscriber here on substack.
Thank you for compiling all of this! I just sent an email.
Excellent oh and Don I want to share positive information on metformin. It’s used to extend life. I’ll share more details on rationale to you but it’s very positive as it turns off mTOR and turns on AMPK it’s to keep cells healthy.